The following research paper and scientific blog are related to our biotechnology platform. For other papers by our scientists visit Other Publications page
Here we show hierarchial forms of a brain-specific phage-derived peptide (herein as NanoLigand Carriers, NLCs) target cerebral endothelial cells through transferrin receptor and the receptor for advanced glycation-end products, cross the blood-brain-barrier and reach neurons and microglial cells.
Wu, L., Ahmadvand, D., Su, J. et al. Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide. Nat Commun 10, 4635 (2019) doi:10.1038/s41467-019-12554-2
Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide